Ignatius Reilly is a fat, lazy, 30-something who lives with his mother, can't keep a job, is paranoid and is writing his life work on Big Chief notepads that he stores under his bed. Other than attending school in Baton Rouge, Reilly hasn't left the New Orleans French quarter, where he has some spectacular encounters with a stripper, a "flamer," a nightclub owner, an elderly secretary and a policeman who is trying to arrest him. A Confederacy of Dunces is a comedy of errors! The story is fun and funny and a tiny bit irritating. Ignatius is a Louisiana cross between Kramer and George Costanza, sarcastic and obtuse.
I can't think of any book like it, but if you're a fan of Seinfeld you should give it a read.