This book is so far out of my traditional reading material that I'm only providing a brief overview. First, it seems to be a comic book novel style and second, it is written in first-person present, which doesn't generally bode well but works in this book.
Calvin "Mechani-Cal" Stringel is a self-proclaimed mediocre supervillain. Actually, he doesn't seem to be a villain at all, but rather a mid-level superhero with sketchy boundaries. Some strange bugs have invaded his futuristic world that are attaching themselves to people and making them bug addicts. Because Cal is protected in his mechanical suit, he has remained unaffected by the bugs, making him responsible to rescue the "superheroes" and get them back to saving the world.
Confessions of a D-List Supervillain was a rather enjoyable step outside of my reading box and a book I'd recommend to YA guys, but not too YA given the graphic romance bit.